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NDesign

ndesign
"NDesign" is a software program for study design for the detection of rare variants from next-generation sequencing (NGS) data.

Last update
2012-06-30

Publication
Sugaya, Y., Akazawa, Y., Saito, A., and Kamitsuji, S. (2012). NDesign: software for study design for the detection of rare variants from next-generation sequencing data. Journal of Human Genetics 57, 676-678.

User's guide download
User's Guide (NDesignGuide.pdf) are available for download.

Conatact
We appreciate your kindness of making contact with Yuki Sugaya; sugaya[at mark]stagen.co.jp (please change [at mark] to @).


Design of Optimal Depth of Coverage

Optimal Depth Calling Error Probability
Significance Level
Pool Size (#carriers of variant )
Desired Power
Max Depth






Design of Experiment

Total Sequence bp
NGS Platform Hiseq2000 5500SOLiD custom
GAIIx GS FLX

Sequencing Method Single-end Read bp
Paired-end Read bp


Gene Length bp
Target Gene Whole genome
Whole exon
ADME gene
custom